The human immune system develops new allergies over a lifetime through sensitization
the verdict
SUPPORTED
the evidence backs this
confidence 85/100
Clinical and immunological studies confirm that the human immune system can become sensitized to new allergens and develop de novo allergic diseases over a lifetime.
Evidence for · 4
Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond.
2024 · cited by 35
Discusses how human germline variants drive severe allergic disease and how immune dysregulation informs fundamental mechanisms of allergic sensitization.
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More for · 3
In search of a new paradigm: mechanisms of sensitization and elicitation of food allergy*
2005 · cited by 20
Highlights research priorities into mechanisms of sensitization and the immune response to food allergens over time.
Adult-onset IgE-mediated food allergy at a Winnipeg allergy clinic: a case series
2020 · cited by 6
Documents clinical cases of adult-onset IgE-mediated food allergy, demonstrating that allergies can develop later in life.
Food protein-induced enterocolitis syndrome in adults: review and practice recommendations
2024 · cited by 1
Shows that allergic conditions like food protein-induced enterocolitis syndrome can develop de novo in adulthood.