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the claim
The Hodgkin-Huxley model accounts for the action of ion pumps such as Na-K-ATPase
the verdict
REFUTED
the evidence says no
confidence 10/100

The classic Hodgkin-Huxley model only accounts for specific voltage-gated sodium and potassium currents and does not natively incorporate ion pumps such as the Na-K-ATPase, which must be added externally in extended models.

Evidence against · 2
Spike–frequency adaptation is modulated by interacting currents in an Hodgkin-Huxley-type model: Role of the Na,K–ATPase
2020 · cited by 0
The study notes that extended Hodgkin-Huxley-type models can incorporate the Na,K-ATPase to study adaptation, confirming it is an addition rather than a feature accounted for by the original model.
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More against · 1
Beyond Hodgkin and Huxley: Calcium and Calcium-Dependent Potassium Currents
1998 · cited by 0
The historical overview explicitly states that the classic Hodgkin-Huxley model equations do not capture—nor were they intended to capture—important phenomena beyond the fast sodium and delayed potassium currents.
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first checked01 Aug 2026
judged → REFUTED · 1001 Aug 2026
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