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the claim

Smoking increases the risk of blood clots and stroke.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that smoking increases the risk of blood clots and stroke?

Yes. Current medical and epidemiological evidence consistently demonstrates that smoking is an independent modifiable risk factor that increases the likelihood of blood clots and stroke.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked

The analysis

The provided retrieved papers include multiple clinical studies establishing a significant statistical association between smoking and vascular thrombotic events, including venous thromboembolism and stroke-related complications. No papers refute the claim.

Evidence for · 3
Risk Factors for Pregnancy-Associated Venous Thromboembolism: The Role of Maternal Age, Obesity, Smoking and Other Modifiable Risk Factors
2018
This study found that smoking is a significant independent risk factor for pregnancy-associated venous thromboembolism (blood clots).
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Kohli, R., Moliterno, A. R., Streiff, M. B., DeBaun, M. R., Kickler, T. S., Blakemore, K., & Chaturvedi, S. (2018). Risk Factors for Pregnancy-Associated Venous Thromboembolism: The Role of Maternal Age, Obesity, Smoking and Other Modifiable Risk Factors. doi.org. https://doi.org/10.1182/blood-2018-99-113599

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More for · 2
Plasma level of human epididymis protein 4 is associated with risk of future venous thromboembolism-the Trøndelag Health study.
2026
This study noted that smoking elevates levels of biomarkers like human epididymis protein 4 and oxidative stress markers, which are associated with an increased risk of venous thromboembolism.
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CJ, C., ES, W. E., TH, N., KD, H., W, T., W, G., AR, F., C, J., L, T., K, H., SK, B., & JB, H. (2026). Plasma level of human epididymis protein 4 is associated with risk of future venous thromboembolism-the Trøndelag Health study.. doi.org. https://doi.org/10.1016/j.jtha.2026.03.009

Incidence, Predictors, and Outcomes of Symptomatic Intracranial Hemorrhage after Tenecteplase in Acute Ischemic Stroke.
2026
This multicenter study identified smoking as an independent predictor of symptomatic intracranial hemorrhage and adverse outcomes following acute ischemic stroke treatment.
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A, D., U, C., S, G., S, B., C, M., A, S., D, D., R, K., SM, D., AP, J., S, D., SK, D., C, B., S, G., B, B., S, S., S, S., S, G., NC, M., SS, D., S, S., M, B., & BK, R. (2026). Incidence, Predictors, and Outcomes of Symptomatic Intracranial Hemorrhage after Tenecteplase in Acute Ischemic Stroke.. doi.org. https://doi.org/10.4103/aian.aian_6_26

What does the evidence say?

The provided retrieved papers include multiple clinical studies establishing a significant statistical association between smoking and vascular thrombotic events, including venous thromboembolism and stroke-related complications. No papers refute the claim.

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