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the claim

Serum cholesterol predicts coronary heart disease in men.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that serum cholesterol predicts coronary heart disease in men?

Yes. Extensive prospective and causal evidence confirms that serum cholesterol levels strongly predict coronary heart disease and ischemic cardiovascular outcomes.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked

The analysis

The retrieved papers consistently support the claim that serum cholesterol is a major predictor of coronary heart disease and ischemic heart disease. Papers 0, 2, and 3 explicitly provide empirical and causal evidence connecting total cholesterol, LDL, and remnant cholesterol to cardiovascular events in men and general populations. Therefore, the balance verdict is SUPPORTED.

Evidence for · 3
Elevated Remnant Cholesterol Causes Both Low-Grade Inflammation and Ischemic Heart Disease, Whereas Elevated Low-Density Lipoprotein Cholesterol Causes Ischemic Heart Disease Without Inflammation
2013
Demonstrates that elevated low-density lipoprotein cholesterol and remnant cholesterol are causally associated with ischemic heart disease.
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Varbo, A., Benn, M., Tybjærg-Hansen, A., & Nordestgaard, B. G. (2013). Elevated Remnant Cholesterol Causes Both Low-Grade Inflammation and Ischemic Heart Disease, Whereas Elevated Low-Density Lipoprotein Cholesterol Causes Ischemic Heart Disease Without Inflammation. doi.org. https://doi.org/10.1161/circulationaha.113.003008

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More for · 2
Do Total and High Density Lipoprotein Cholesterol and Triglycerides Act Independently in the Prediction of Ischemic Heart Disease?
2001
Shows that total cholesterol and other lipids are strongly and independently predictive of ischemic heart disease in men over a 10-year follow-up.
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Yarnell, J., Patterson, C., Sweetnam, P., Thomas, H., Bainton, D., Elwood, P., Bolton, C., & Miller, N. (2001). Do Total and High Density Lipoprotein Cholesterol and Triglycerides Act Independently in the Prediction of Ischemic Heart Disease?. doi.org. https://doi.org/10.1161/hq0801.093505

Total cholesterol and mortality from ischemic heart disease and overall cardiovascular disease in Korean adults
2019
Finds that total cholesterol is positively associated with cardiovascular and ischemic heart disease mortality in the upper range among adults.
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Kwon, D., Yi, J., Ohrr, H., & Yi, S. (2019). Total cholesterol and mortality from ischemic heart disease and overall cardiovascular disease in Korean adults. doi.org. https://doi.org/10.1097/md.0000000000017013

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