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Psychological stress increases the risk of stroke.
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SUPPORTED
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8 sources for · 0 against
Is it true that psychological stress increases the risk of stroke?
Yes. Two large meta-analyses (28 studies, over 950,000 participants; 84 studies, over 4 million participants) report that psychological stress is associated with roughly 27-46% higher stroke risk, and a veterans cohort links PTSD to increased ischemic stroke risk.
Verdict: SUPPORTED · 8 sources for, 0 against · Last checked
Evidence for · 8
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Psychological stress. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Psychological_stress
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More for · 7
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Stress and Stroke: Psychological Approach Patients in Middle Hospitalier. (2020). u-picardie.hal.science. https://doi.org/10.4236/ojmp.2020.93007
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Khalifa, M. A., Alardhi, A. S., Alharbi, G. F. S., Alzahrani, A. M. M., Taqi, B. A., & Alsalman, F. S. (2025). Psychosocial stress and stroke risk: meta-analysis of observational studies. doi.org. https://doi.org/10.3389/fneur.2025.1669925
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Psychosocial stress and stroke risk: meta-analysis of observational studies - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.3389/fneur.2025.1669925
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MA, K., D, H., AAI, A., AS, G., DE, A., ARA, Z., EA, M., MA, G., MH, A., MM, A., OA, I., AM, A., AF, A., HA, A., MM, G., & MH, K. (2026). Psychosocial stress and risk of first-ever stroke: a systematic review and meta-analysis.. doi.org. https://doi.org/10.1186/s12883-026-05307-4
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Rosman, L., Sico, J. J., Lampert, R., Gaffey, A., Ramsey, C., Dziura, J., Chui, P. W., Cavanagh, C. E., Brandt, C., Haskell, S., & Burg, M. (2019). Posttraumatic Stress Disorder and Risk for Stroke in Young and Middle-Aged Adults: A 13-Year Cohort Study.. doi.org. https://doi.org/10.1161/STROKEAHA.119.026854
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A Randomized Placebo-controlled Trial of Methylphenidate in Veterans With a Diagnosis of Post Traumatic Stress Disorder and Recent Cerebral Stroke. (2022). clinicaltrials.gov. https://clinicaltrials.gov/study/NCT04885257
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Marvar, P. & Harrison, D. (2012). Stress-Dependent Hypertension and the Role of T Lymphocytes. doi.org. https://doi.org/10.1113/expphysiol.2011.061507
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Fekadu, G. (2019). Current challenges and strategies in management and prevention of stroke. doi.org. https://doi.org/10.15406/jnsk.2019.09.00366
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