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the claim

Peter Medawar proposed the mutation accumulation hypothesis in 1952.

the verdict

SUPPORTED

the evidence backs this

Recorded sources

7 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Peter Medawar proposed the mutation accumulation hypothesis in 1952?

Yes. Multiple reliable reference and academic sources confirm that Peter Medawar proposed the mutation accumulation hypothesis in 1952.

Verdict: SUPPORTED · 7 sources for, 0 against · Last checked 4 Oct 2026

How claims like this are judged

Judged against reference works: claims of this kind are settled by the historical reference record, not journal abstracts.

Evidence for · 7

Wikipedia: Mutation accumulation theory

Reference article covering this claim directly

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Wikipedia: Mutation accumulation theory. (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Mutation_accumulation_theory

2 recorded entries grouped as this source

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Wikipedia: Wikipedia: Mutation accumulation theory

Confirms the mutation accumulation theory was first proposed by Peter Medawar in 1952.

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Wikipedia: Wikipedia: Mutation accumulation theory. (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Mutation_accumulation_theory

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More for · 6

Wikipedia: Evolution of ageing

Reference article covering this claim directly

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Wikipedia: Evolution of ageing. (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Evolution_of_ageing

Wikipedia: Senescence

Reference article covering this claim directly

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Wikipedia: Senescence. (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Senescence

LibreTexts: LibreTexts: 3: The Evolution of Aging

Explicitly states Peter Medawar formalized this observation in his mutation accumulation hypothesis.

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LibreTexts: LibreTexts: 3%3A The Evolution of Aging. (n.d.). LibreTexts. https://bio.libretexts.org/Courses/CT_State_Northwestern/General_Ecology_Ecology/Chapter_8%3A_Life_Histories/3%3A_The_Evolution_of_Aging

Semantic Scholar peS2o: Evolutionary Theories of Aging and Longevity

Identifies the mutation accumulation theory of aging as suggested by Peter Medawar.

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Semantic Scholar peS2o: Evolutionary Theories of Aging and Longevity. (n.d.). Semantic Scholar peS2o. http://downloads.hindawi.com/journals/tswj/2002/704240.pdf

Simple English Wikipedia: Simple English Wikipedia: George C. Williams

Notes the idea was proposed by Peter Medawar in his 1952 publication.

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Simple English Wikipedia: Simple English Wikipedia: George C. Williams. (n.d.). Simple English Wikipedia. https://simple.wikipedia.org/wiki/George_C._Williams

LibreTexts: LibreTexts: 8.04: The Evolution of Aging

States Peter Medawar formalized this observation in his mutation accumulation hypothesis.

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LibreTexts: LibreTexts: 8.04%3A The Evolution of Aging. (n.d.). LibreTexts. https://bio.libretexts.org/Courses/Gettysburg_College/01%3A_Ecology_for_All/08%3A_Life_Histories/8.04%3A_The_Evolution_of_Aging

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