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the claim
Paracetamol lowers body temperature in people with a fever.
the verdict
INSUFFICIENT LEANING
Recorded sources
7 sources for · 0 against
Is it true that Paracetamol lowers body temperature in people with a fever?
Unclear. Several sources indicate paracetamol is an antipyretic that lowers body temperature, including a clinical guideline recommending acetaminophen for febrile children and a stroke trial reporting reduced temperature after paracetamol. However, these cover specific populations or general drug classifications rather than directly establishing the general claim that paracetamol lowers fever.
Verdict: PARTIAL LEAN · 7 sources for, 0 against · Last checked
Evidence for · 7
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Jonge, J. C. d., Sluis, W. M., Reinink, H., Bath, P., Woodhouse, L. J., & Beek, D. v. d. (2026). The effects of prophylactic use of paracetamol on body temperature and blood pressure in elderly patients with acute stroke: Data from the PRECIOUS trial. doi.org. https://doi.org/10.1371/journal.pone.0342937
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More for · 6
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T, N., H, K., J, S., S, S., R, M., & D, M. (2026). Clinical Practice Guideline: The Outpatient Management of Fever in Children and Adolescents.. doi.org. https://doi.org/10.3238/arztebl.m2026.0002
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P, K., D, A., N, B., I, K., C, M., & GI, B. (2013). Fever effects and treatment in critical care: literature review.. doi.org. https://doi.org/10.1016/j.aucc.2012.10.004
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A.X., X., D.B., B., & M.A., A. (2026). PHARMACOLOGICAL STUDY OF PARACETAMOL METABOLISM AND ITS HEPATOTOXIC EFFECTS (LITERATURE REVIEW). zenodo.org. https://doi.org/10.5281/zenodo.22877381
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What You Should Know About Medicines/Antipyretic. (n.d.). en.wikibooks.org. https://en.wikibooks.org/wiki/What_You_Should_Know_About_Medicines/Antipyretic
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Paracetamol therapy and outcome of critically ill patients: a multicenter retrospective observational study. (n.d.). cir.nii.ac.jp. https://doi.org/10.1186/s13054-015-0865-1
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Lewis, S. R., Baker, P. E., Andrews, P. J., Cheng, A., Deol, K., Hammond, N., & Saxena, M. (2020). Interventions to reduce body temperature to 35 ⁰C to 37 ⁰C in adults and children with traumatic brain injury.. doi.org. https://doi.org/10.1002/14651858.CD006811.pub4
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