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Osteoarthritis is linked to type 2 diabetes.
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SUPPORTED
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7 sources for · 0 against
Is it true that osteoarthritis is linked to type 2 diabetes?
Yes. A peer-reviewed review reports that type 2 diabetes has a pathogenic effect on osteoarthritis and is a risk factor for its progression, and a reference source notes diabetes doubles the risk of osteoarthritis-related joint replacement. Other studies describe shared metabolic mechanisms and co-occurrence of the two conditions.
Verdict: SUPPORTED · 7 sources for, 0 against · Last checked
Evidence for · 7
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Osteoarthritis. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Osteoarthritis
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More for · 6
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Type 2 diabetes mellitus and osteoarthritis. (2019). hal.sorbonne-universite.fr. https://doi.org/10.1016/j.semarthrit.2019.01.005
2 recorded entries grouped as this source
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Type 2 diabetes mellitus and osteoarthritis - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1016/j.semarthrit.2019.01.005
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Insulin Resistance in Osteoarthritis and Type 2 Diabetes Mellitus. (2021). hal.science. https://hal.science/hal-05266879v1
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Tchetina, E. V., Markova, G. A., & Sharapova, E. P. (2020). Insulin Resistance in Osteoarthritis: Similar Mechanisms to Type 2 Diabetes Mellitus. doi.org. https://doi.org/10.1155/2020/4143802
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Yang, Y., Wang, Y., Kong, Y., Zhang, X., Zhang, H., & Gang, Y. (2018). Carnosine Prevents Type 2 Diabetes-Induced Osteoarthritis Through the ROS/NF-κB Pathway. doi.org. https://doi.org/10.3389/fphar.2018.00598
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Hu, H., Zhou, C., Jiang, B., Wu, S., Cai, T., & Yu, J. (2025). Expression and clinical significance of LncRNA Kcnq1ot1 in type 2 diabetes mellitus patients with osteoarthritis. doi.org. https://doi.org/10.1186/s12902-025-01915-2
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Higher intakes of nutrients are linked with a lower risk of cardiovascular diseases, type 2 diabetes mellitus, arthritis, and depression among Korean adults. (2022). doi.org. https://doi.org/10.1016/j.nutres.2021.11.003
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