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Mutations can be inherited from parents.

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SUPPORTED
the evidence backs this
Recorded sources
10 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that mutations can be inherited from parents?

Yes. Multiple reference and review sources state that germline mutations are passed from parent to child and down generations, while somatic mutations are not inherited. Several case reports and disease studies also document mutations inherited from parents in specific conditions.

Verdict: SUPPORTED · 10 sources for, 0 against · Last checked

Evidence for · 10
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Mutation. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Mutation

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More for · 9
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inherited. (n.d.). cancer.gov. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/inherited

2020
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Whether de novo mutation can be inherited or not?. (2020). biology.stackexchange.com. https://biology.stackexchange.com/questions/90515/whether-de-novo-mutation-can-be-inherited-or-not

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Mechanisms for variable expressivity of inherited SCN1A mutations causing Dravet syndrome. (n.d.). cir.nii.ac.jp. https://doi.org/10.1136/jmg.2009.074328

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PubMed: [Single-parent inheritance of mitochondrial mutations resistant to tetracycline in Saccharomyces cerevisiae].. (n.d.). pubmed.ncbi.nlm.nih.gov. https://pubmed.ncbi.nlm.nih.gov/767203/

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INHERIT EGFR - INvestigating HEreditary RIsk From T790M: A Multi-Centered Study to Identify and Characterize Individuals Carrying Germline EGFR Mutations. (n.d.). clinicaltrials.gov. https://clinicaltrials.gov/study/NCT01754025

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Wikibooks: Handbook of Genetic Counseling/Rett Syndrome. (n.d.). en.wikibooks.org. https://en.wikibooks.org/wiki/Handbook_of_Genetic_Counseling/Rett_Syndrome

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What Is a Genetic Mutation? Definition & Types. (n.d.). my.clevelandclinic.org. https://my.clevelandclinic.org/health/body/23095-genetic-mutations-in-humans

2020
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First case of fetal goitrous hypothyroidism due to SLC5A5/NIS mutations. (2020). hal.science. https://doi.org/10.1530/eje-20-0255

2024
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Samir, S. (2024). Human DNA Mutations and their Impact on Genetic Disorders.. doi.org. https://doi.org/10.2174/0118722083255081231020055309

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