Multiple sclerosis causes headaches, including migraines, more often than in people without the disease.

Is it true that multiple sclerosis causes headaches, including migraines, more often than in people without the disease?

Unclear. Several sources report that headaches, especially migraine, are common in people with multiple sclerosis, including a pediatric cohort and a first-manifestation study. However, none of the retrieved items provides a direct comparison of headache prevalence in MS patients versus people without the disease, so the comparative part of the claim is only partially covered.

Verdict: PARTIAL LEAN · 4 sources for, 0 against · Last checked 3 Oct 2026

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

G, T., G, M., MAN, F., F, U., G, S., C, R., G, M., A, B., M, V., & L, P. (2025). Pediatric-Onset Multiple Sclerosis and Primary Headache: Is There a Link?. doi.org. https://doi.org/10.3390/children12080963

Pakpoor, J., Handel, A. E., Giovannoni, G., Dobson, R., & Ramagopalan, S. V. (2012). Meta-Analysis of the Relationship between Multiple Sclerosis and Migraine. doi.org. https://doi.org/10.1371/journal.pone.0045295

Headache in the first manifestation of Multiple Sclerosis – Prospective, multicenter study - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1002/brb3.852

G.S., M. & M.I., A. (2023). Impact of comorbid primary headache on neurological function of patients with multiple sclerosis. zenodo.org. https://doi.org/10.5281/zenodo.15584989