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the claim

Monocyte-derived macrophages are a nondividing cell type that serves as a natural target for HIV infection.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Monocyte-derived macrophages are a nondividing cell type that serves as a natural target for HIV infection?

Yes. Monocyte-derived macrophages are terminally differentiated, nondividing cells that serve as natural target cells for HIV infection.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked

The analysis

The retrieved literature consistently identifies macrophages as terminally differentiated, nondividing cells that are key natural targets for HIV infection and susceptible to viral transduction.

Evidence for · 3
Caffeine Inhibits Human Immunodeficiency Virus Type 1 Transduction of Nondividing Cells
2005
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Daniel, R., Marusich, E., Argyris, E., Zhao, R. Y., Skalka, A. M., & Pomerantz, R. J. (2005). Caffeine Inhibits Human Immunodeficiency Virus Type 1 Transduction of Nondividing Cells. doi.org. https://doi.org/10.1128/jvi.79.4.2058-2065.2005

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More for · 2
Cellular Restriction Targeting Viral Capsids Perturbs Human Immunodeficiency Virus Type 1 Infection of Nondividing Cells
2009
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Yamashita, M. & Emerman, M. (2009). Cellular Restriction Targeting Viral Capsids Perturbs Human Immunodeficiency Virus Type 1 Infection of Nondividing Cells. doi.org. https://doi.org/10.1128/jvi.01084-09

Enhanced infection efficiency and cytotoxicity mediated by vpx-containing lentivirus in chimeric antigen receptor macrophage (CAR-M).
2023
Get citation
Y, G., Y, J., X, R., L, Z., & X, Y. (2023). Enhanced infection efficiency and cytotoxicity mediated by vpx-containing lentivirus in chimeric antigen receptor macrophage (CAR-M).. doi.org. https://doi.org/10.1016/j.heliyon.2023.e21886

What does the evidence say?

The retrieved literature consistently identifies macrophages as terminally differentiated, nondividing cells that are key natural targets for HIV infection and susceptible to viral transduction.

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