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the claim

MicroRNAs can regulate gene expression by causing mRNA degradation or blocking translation.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
7 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that MicroRNAs can regulate gene expression by causing mRNA degradation or blocking translation?

Yes. MicroRNAs regulate gene expression post-transcriptionally by binding to target messenger RNAs, leading to transcript degradation or translational repression.

Verdict: SUPPORTED · 7 sources for, 0 against · Last checked

The analysis

The claim states that microRNAs regulate gene expression by causing mRNA degradation or blocking translation. Multiple retrieved papers explicitly support that microRNAs act post-transcriptionally by targeting mRNAs to suppress their expression and regulate stability.

Evidence for · 7
Spatiotemporal Control of microRNA-Target Interactions.
2026
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LTT, L. (2026). Spatiotemporal Control of microRNA-Target Interactions.. doi.org. https://doi.org/10.1002/wrna.70053

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More for · 6
Noncoding RNAs and the Architecture of Gene Regulation: Focus on Long and Small Regulatory RNAs.
2026
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SZ, D., SK, B., & CS, L. (2026). Noncoding RNAs and the Architecture of Gene Regulation: Focus on Long and Small Regulatory RNAs.. doi.org. https://doi.org/10.1002/wrna.70051

Impact of <i>miR-1/miR-133</i> Cluster in Cardiogenesis and Heart Failure.
2026
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C, G., E, L., V, G., A, A., D, F., V, G., & C, L. (2026). Impact of <i>miR-1/miR-133</i> Cluster in Cardiogenesis and Heart Failure.. doi.org. https://doi.org/10.3390/jcdd13080376

The Promise and Pursuit of MicroRNAs for Cancer Treatment.
2026
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C, B., A, R., J, K., & JJ, L. (2026). The Promise and Pursuit of MicroRNAs for Cancer Treatment.. doi.org. https://doi.org/10.3390/biom16081086

A Mathematical Approach on the Limits of ceRNA Hypothesis Through an Ordinary Differential Equations (ODE) Model of mRNA-microRNA Interactions.
2026
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P, F., M, O., R, S., CE, M., & C, V. (2026). A Mathematical Approach on the Limits of ceRNA Hypothesis Through an Ordinary Differential Equations (ODE) Model of mRNA-microRNA Interactions.. doi.org. https://doi.org/10.3390/ncrna12040022

MicroRNA circuits and regulatory networks: emerging therapeutic paradigm.
2026
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S, G. & S, S. (2026). MicroRNA circuits and regulatory networks: emerging therapeutic paradigm.. doi.org. https://doi.org/10.1080/15476286.2026.2731890

The Hidden Layer of MicroRNA Regulation in Gynecologic Cancers: IsomiRs, Arm Switching, and RNA Epitranscriptomic Modifications.
2026
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Y, P., C, L., LC, F., ME, A., A, C. R., & YM, S. (2026). The Hidden Layer of MicroRNA Regulation in Gynecologic Cancers: IsomiRs, Arm Switching, and RNA Epitranscriptomic Modifications.. doi.org. https://doi.org/10.3390/ijms27167363

What does the evidence say?

The claim states that microRNAs regulate gene expression by causing mRNA degradation or blocking translation. Multiple retrieved papers explicitly support that microRNAs act post-transcriptionally by targeting mRNAs to suppress their expression and regulate stability.

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