Long-term residence on the ISS causes negative effects on human eyesight.
the verdict
SUPPORTED
the evidence backs this
confidence 75/100
Long-term residence on the ISS causes well-documented negative effects on human eyesight, frequently resulting in spaceflight-associated neuro-ocular syndrome (SANS), optic disc edema, globe flattening, and hyperopic shifts.
Evidence for · 6
Ophthalmic and Visual System Changes in Human Spaceflight: A Review of Mechanisms, Measurement, and Countermeasures.
2026 · cited by 0
Reviews evidence showing that long-duration spaceflight induces lasting ocular complications and visual impairments.
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More for · 5
Asymmetric Optic Disc Edema in Astronauts: A Narrative Review Proposing an Interplay Between Ocular Venous Congestion and Glymphatic Transport.
2026 · cited by 0
Discusses spaceflight-associated neuro-ocular syndrome (SANS) as a significant ophthalmic complication during and after missions.
Ocular health in outer space and beyond gravity: A minireview.
2026 · cited by 0
Notes that approximately one-third of astronauts experience SANS, featuring optic disc edema and hyperopic shifts during long missions.
AstroOphthalmology: Basic and Pathophysiological Concepts of Space-Induced Ocular Changes.
2026 · cited by 0
Highlights that microgravity and cosmic radiation synergistically cause visual dysfunction and ocular pathologies.
Physiological cerebrospinal fluid interactions between brain and eye structures are altered after long-duration spaceflight.
2026 · cited by 0
Demonstrates that long-duration spaceflight alters cerebrospinal fluid interactions, leading to measurable structural eye changes.
Spaceflight stressors impact on mitochondrial function and the risk for development of ocular pathology.
2026 · cited by 0
Links microgravity-induced mitochondrial dysfunction and oxidative stress in ocular tissues to spaceflight ocular pathology.