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the claim
Kinase enzymes remove phosphate groups from proteins.
the verdict
REFUTED
the evidence says no
Recorded sources
0 sources for · 9 against
Is it true that Kinase enzymes remove phosphate groups from proteins?
No. Multiple reference and textbook sources state that kinases add phosphate groups to proteins (phosphorylation), while phosphatases are the enzymes that remove phosphate groups (dephosphorylation). The claim reverses these roles, so the evidence refutes it.
Verdict: REFUTED · 0 sources for, 9 against · Last checked
Evidence against · 9
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Why don't phosphatases both add and remove phosphate groups if enzymes catalyze reactions in both directions?. (2018). biology.stackexchange.com. https://biology.stackexchange.com/questions/77049/why-dont-phosphatases-both-add-and-remove-phosphate-groups-if-enzymes-catalyze
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More against · 8
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Bag, J. & Sells, B. (1979). The presence of protein kinase activity and acceptors of phosphate groups in nonpolysomal cytoplasmic messenger ribonucleoprotein complexes of embryonic chicken muscle.. doi.org. https://doi.org/10.1016/s0021-9258(18)50730-4
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Widmaier, E. P., Raff, H., & Strang, K. T. (2008). Vander's Human Physiology. books.google.com. http://books.google.com/books?id=7GRqAAAAMAAJ&dq=Kinase+enzymes+remove+phosphate+groups+from+proteins.&hl=&as_pt=BOOKS&source=gbs_api
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Kinase - Wikipedia. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Kinase
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Ghatge, M. S., Contestabile, R., Salvo, M. L. d., Desai, J. V., Gandhi, A. K., & Camara, C. M. (2012). Pyridoxal 5′-Phosphate Is a Slow Tight Binding Inhibitor of E. coli Pyridoxal Kinase. doi.org. https://doi.org/10.1371/journal.pone.0041680
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Non-Receptor Type Protein Tyrosine Phosphatase. (n.d.). purl.obolibrary.org. http://purl.obolibrary.org/obo/NCIT_C106408
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Structural Biochemistry/Kinase. (n.d.). en.wikibooks.org. https://en.wikibooks.org/wiki/Structural_Biochemistry/Kinase
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Protein Tyrosine Phosphatase. (n.d.). purl.obolibrary.org. http://purl.obolibrary.org/obo/NCIT_C17444
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Protein Tyrosine Phosphatase Gene. (n.d.). purl.obolibrary.org. http://purl.obolibrary.org/obo/NCIT_C26059
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