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Influenza infection can lead to sepsis.
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SUPPORTED
the evidence backs this
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7 sources for · 0 against
Is it true that influenza infection can lead to sepsis?
Yes. The CDC states that influenza virus infection of the respiratory tract can trigger an extreme inflammatory response and lead to sepsis. Additional case reports and research describe sepsis or viral sepsis occurring secondary to influenza A/H1N1 infection, though these are narrower in scope.
Verdict: SUPPORTED · 7 sources for, 0 against · Last checked
Evidence for · 7
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Influenza. (n.d.). wikem.org. https://wikem.org/wiki/Influenza
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More for · 6
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Zheng, Y., He, D., Zuo, W., Wang, W., Wu, K., Wu, H., Yuan, Y., Huang, Y., Li, H., Lu, Y., Zhao, L., Wang, X., Wang, J., Zhang, Y., Zou, G., Li, H., Wang, Z., & Cao, B. (2025). Influenza A virus dissemination and infection leads to tissue resident cell injury and dysfunction in viral sepsis. doi.org. https://doi.org/10.1016/j.ebiom.2025.105738
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Signs and Symptoms of Flu | Influenza (Flu) | CDC. (n.d.). cdc.gov. https://www.cdc.gov/flu/signs-symptoms/index.html
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Cano-Gamez, E., Burnham, K., Goh, C., Allcock, A., Malick, Z. H., Overend, L., Kwok, A., Smith, D. A., Peters-Sengers, H., Antcliffe, D., Mckechnie, S., Scicluna, B., Poll, T. v. d., Gordon, A., Hinds, C., Davenport, E., Knight, J., Webster, N., Galley, H., & Taylor, J. (2022). An immune dysfunction score for stratification of patients with acute infection based on whole blood gene expression. doi.org. https://doi.org/10.1126/scitranslmed.abq4433
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An immune dysfunction score for stratification of patients with acute infection based on whole blood gene expression. (2022). doi.org. https://doi.org/10.1101/2022.03.17.22272427
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Wang, X., Ma, X., Zeng, Y., & Li, C. (2025). Unusual neutrophilic morphology in influenza-A-induced septic shock: Blue-green inclusions and phagocytosis of autologous cells in a toddler. doi.org. https://doi.org/10.3389/fcimb.2025.1684054
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[Pneumonia and the acute respiratory distress syndrome due to influenza A (H1N1) virus].. (2010). pubmed.ncbi.nlm.nih.gov. https://pubmed.ncbi.nlm.nih.gov/19854543
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