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the claim

Increased UV exposure is associated with an increased risk of melanoma incidence and melanoma death.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 1 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that increased UV exposure is associated with an increased risk of melanoma incidence and melanoma death?

Yes. Robust epidemiological and mechanistic evidence indicates that increased ultraviolet radiation exposure significantly raises the risk of cutaneous melanoma, even though genetic factors like depigmentation also play a major modulating role.

Verdict: SUPPORTED · 3 sources for, 1 against · Last checked

Evidence for · 3
Ultraviolet A radiation exposure and melanoma: a review
2022
The review details how ultraviolet radiation (both UVA and UVB) induces oxidative stress, DNA mutations, and is positively associated with melanoma development on molecular and epidemiological levels.
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Fadadu, R. P. & Wei, M. L. (2022). Ultraviolet A radiation exposure and melanoma: a review. doi.org. https://doi.org/10.1097/cmr.0000000000000857

Evidence against · 1
Evolved adaptation to low ultraviolet radiation may be the main cause of malignant melanoma independent of high ultraviolet radiation exposure
2020
This ecological study suggests that genetically determined low melanin production and depigmentation, rather than high ultraviolet radiation exposure, are the primary determinants of malignant melanoma incidence.
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You, W., Henneberg, R. J., Coventry, B., & Henneberg, M. (2020). Evolved adaptation to low ultraviolet radiation may be the main cause of malignant melanoma independent of high ultraviolet radiation exposure. doi.org. https://doi.org/10.21203/rs.3.rs-28249/v1

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More for · 2
Global patterns of melanoma, burden attributable to ultraviolet radiation exposure, and projections to 2050 across 185 countries: A population-based study with global modeling.
2026
The global population-based study estimates that approximately 88% of new melanoma cases are attributable to ultraviolet radiation exposure.
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J, O., S, K., SH, H., Y, S., J, L., J, K., GF, L. S., D, P., J, H., & DK, Y. (2026). Global patterns of melanoma, burden attributable to ultraviolet radiation exposure, and projections to 2050 across 185 countries: A population-based study with global modeling.. doi.org. https://doi.org/10.1016/j.jdin.2026.05.026

Occupational solar UV-exposure and risk of cutaneous melanoma among Danish workers: A nationwide cohort study.
2026
The nationwide cohort study demonstrates an exposure-response relationship where occupational solar ultraviolet radiation exposure significantly increases cutaneous melanoma incidence.
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I, K., SAJ, S., AW, G., IB, I., M, F., ET, W., MC, T., K, G., HA, K., & ZA, S. (2026). Occupational solar UV-exposure and risk of cutaneous melanoma among Danish workers: A nationwide cohort study.. doi.org. https://doi.org/10.1016/j.ejca.2026.116884

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