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the claim
If one parent has Huntington's disease, their child has a 50% chance of inheriting the disease.
the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against
Is it true that if one parent has Huntington's disease, their child has a 50% chance of inheriting the disease?
Yes. Huntington's disease is an autosomal dominant genetic disorder, meaning that a child who has one affected parent faces a 50% statistical chance of inheriting the mutated gene.
Verdict: SUPPORTED · 3 sources for, 0 against · Last checked
The analysis
Huntington's disease is a classic example of an autosomal dominant condition. Standard Mendelian genetics dictates that an affected heterozygous parent has a 50% chance of passing the pathogenic allele to each offspring. Retrieved papers 2, 4, and 11 all directly support this principle.
Evidence for · 3
Get citation
Datta, N. (2024). Molecular Mechanisms and Clinical Features of Huntington Disease: A Fatal Neurodegenerative Disorder with Autosomal Dominant Inheritance. doi.org. https://doi.org/10.52214/cusj.v17i1.10288
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More for · 2
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Young, I. d. (1991). Autosomal dominant inheritance. doi.org. https://doi.org/10.1093/oso/9780199632633.003.0003
Get citation
Young, I. D. (1999). Autosomal dominant inheritance. doi.org. https://doi.org/10.1093/oso/9780192629623.003.0002
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