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the claim

Hypothyroidism increases the risk of developing rheumatoid arthritis.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
5 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that hypothyroidism increases the risk of developing rheumatoid arthritis?

Yes. A bidirectional Mendelian randomization study reports that genetically predicted hypothyroidism is causally associated with a higher risk of rheumatoid arthritis (odds ratios around 1.4–1.7). Several cross-sectional and review sources also note higher hypothyroidism or autoimmune thyroiditis prevalence among rheumatoid arthritis patients, though these do not by themselves establish the direction of risk.

Verdict: SUPPORTED · 5 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 5
Hypothyroidism
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Hypothyroidism. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Hypothyroidism

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More for · 4
Prevalence of Hypothyroidism in Rheumatoid Arthritis and its Correlation with Disease Activity
2023
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Prevalence of Hypothyroidism in Rheumatoid Arthritis and its Correlation with Disease Activity. (2023). doi.org. https://doi.org/10.33140/bscr.02.01.02

Frontiers | Rheumatoid arthritis and hypothyroidism: a bidirectional Mendelian randomization study
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Frontiers | Rheumatoid arthritis and hypothyroidism: a bidirectional Mendelian randomization study. (n.d.). frontiersin.org. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1146261/full

Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism
2021
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Shukla, R., Ganeshani, M., Agarwal, M., Jangir, R., Kandel, G., & Sankanagoudar, S. (2021). Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism. doi.org. https://doi.org/10.1371/journal.pone.0246195

TREATMENT OF COMORBID PATHOLOGY IN PATIENTS WITH RHEUMATOID ARTHRITIS
2023
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Zikriyaevna, S. G., Khabibullaevna, S. B., & Khudoiberdievna, S. N. (2023). TREATMENT OF COMORBID PATHOLOGY IN PATIENTS WITH RHEUMATOID ARTHRITIS. zenodo.org. https://doi.org/10.5281/zenodo.10052898

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