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the claim

Gut microbiome composition is linked to depression and anxiety in humans.

the verdict
INSUFFICIENT LEANING
Recorded sources
10 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that gut microbiome composition is linked to depression and anxiety in humans?

Unclear. Multiple reviews and studies report that altered gut microbiome composition is associated with depression and anxiety in humans, though several items are animal or in-vitro work and one review notes robust symptom-biomarker bridging evidence remains limited.

Verdict: PARTIAL LEAN · 10 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 10
Human microbiome
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Human microbiome. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Human_microbiome

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More for · 9
MICROBIOME-GUT-BRAIN AXIS IN DEPRESSION AND ANXIETY DISORDERS
2026
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Mahbubani, S. & Prema, D. K. K. (2026). MICROBIOME-GUT-BRAIN AXIS IN DEPRESSION AND ANXIETY DISORDERS. doi.org. https://doi.org/10.58532/nbennur3174c1

Does Gut Microbiome Composition Influence the Efficacy of Psychiatric Drugs?
2025
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Nadia, S. & K., M. S. (2025). Does Gut Microbiome Composition Influence the Efficacy of Psychiatric Drugs?. authors.library.caltech.edu. https://doi.org/10.33590/emj/cseb2440

Psychobiotic, nutritional, and behavioral interventions targeting the microbiome-gut-brain axis in depression, anxiety, and stress: a scoping review.
2026
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Q, D., C, F., Y, D., H, S., & Z, D. (2026). Psychobiotic, nutritional, and behavioral interventions targeting the microbiome-gut-brain axis in depression, anxiety, and stress: a scoping review.. doi.org. https://doi.org/10.3389/fnut.2026.1856471

Bioengineered Wheat Arabinoxylan: Fostering Next-Generation Prebiotics Targeting Gut Microbiome and Depression Inversely-Linked Microbes
2023
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Bioengineered Wheat Arabinoxylan: Fostering Next-Generation Prebiotics Targeting Gut Microbiome and Depression Inversely-Linked Microbes. (2023). doi.org. https://doi.org/10.20381/ruor-29036

Microbiome-Driven Proline Biogenesis in Plants under Stress: Perspectives for Balanced Diet to Minimize Depression Disorders in Humans
2022
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Vujanovic, S., Vujanovic, J., & Vujanovic, V. (2022). Microbiome-Driven Proline Biogenesis in Plants under Stress: Perspectives for Balanced Diet to Minimize Depression Disorders in Humans. doi.org. https://doi.org/10.3390/microorganisms10112264

Microbiome Dysbiosis in Depression: A Narrative Review
2024
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Microbiome Dysbiosis in Depression: A Narrative Review. (2024). doi.org. https://doi.org/10.31436/imjm.v23i03.2293

Post-stress changes in the gut microbiome composition in rats with different levels of nervous system excitability.
2023
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Shevchenko, A., Shalaginova, I., Katserov, D., Matskova, L., Shiryaeva, N., & Dyuzhikova, N. (2023). Post-stress changes in the gut microbiome composition in rats with different levels of nervous system excitability.. doi.org. https://doi.org/10.1371/journal.pone.0295709

Role of gut microbiota in depression: Understanding molecular pathways, recent research, and future direction
2023
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Role of gut microbiota in depression: Understanding molecular pathways, recent research, and future direction. (2023). doi.org. https://doi.org/10.1016/j.bbr.2022.114081

Effects of B. infantis on the Maternal Restraint Model of Depression
2019
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Barker, S. & Driscoll, L. (2019). Effects of B. infantis on the Maternal Restraint Model of Depression. impulse.appstate.edu. https://impulse.appstate.edu/articles/2019/effects-b-infantis-maternal-restraint-model-depression

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