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the claim
Gabapentin lowers heart rate.
the verdict
INSUFFICIENT LEANING
Recorded sources
5 sources for · 0 against
Is it true that gabapentin lowers heart rate?
Unclear. Animal studies report that gabapentin lowers heart rate in hypertensive rats, and several small clinical trials examined whether preoperative gabapentin blunts the heart-rate rise during intubation, but their retrieved text does not report results. No item establishes a general heart-rate-lowering effect in humans.
Verdict: PARTIAL LEAN · 5 sources for, 0 against · Last checked
Evidence for · 5
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Gabapentin Reduces Blood Pressure and Heart Rate through the Nucleus Tractus Solitarii - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.6515/ACS.201911_35(6).20190429B
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More for · 4
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Hemodynamic Response to Gabapentin in Conscious Spontaneously Hypertensive Rats. (n.d.). cir.nii.ac.jp. https://doi.org/10.1161/hypertensionaha.118.09909
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Bhandari, G. & Shahi, K. (2013). Effect of Gabapentin on Pressor Response to Laryngoscopy and Tracheal Intubation: A Double Blind Randomized Placebo Controlled Study. zenodo.org. https://doi.org/10.5281/zenodo.8262651
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Quraishi, A. N. M. A. (2023). To Study the Efficacy of Oral Gabapentin for Attenuation of the Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation. zenodo.org. https://doi.org/10.5281/zenodo.7947330
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S., M., M., S. G., & Murthy, V. K. (2022). A Comparative Evaluation of Premedication with Oral Gabapentin and Pregabalin in Attenuation of Pressor Response to Endotracheal Intubation under General Anaesthesia. zenodo.org. https://doi.org/10.5281/zenodo.13828708
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