Fecal microbiota transplantation is an effective treatment for Clostridium difficile infection
the verdict
SUPPORTED
the evidence backs this
confidence 79/100
Fecal microbiota transplantation is widely supported by clinical literature, systematic reviews, and professional guidelines as a highly effective and established treatment for recurrent Clostridium difficile infection.
Evidence for · 8
Microbiota-Based Therapies for Recurrent Clostridium difficile Infection: A Systematic Review of Their Efficacy and Safety.
2025 · cited by 3
A systematic review notes that FMT and standardized microbiome therapeutics demonstrate superior clinical cure rates compared to traditional therapies for recurrent Clostridioides difficile infection.
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More for · 7
15-strain live biotherapeutic product or same donor fecal microbiota transplant for recurrent Clostridioides difficile infection: a randomized phase 1b trial.
2026 · cited by 1
A randomized phase 1b trial demonstrates that fecal microbiota transplant effectively prevents recurrent Clostridioides difficile infection.
Fecal Microbiota Transplantation in 2025: Two Steps Forward, One Step Back.
2026 · cited by 1
A review highlights that FMT has been integrated into routine algorithms and clinical guidelines for treating Clostridioides difficile infection following extensive supportive evidence and recent FDA approvals.
Restoring Microbial Balance: Clinical Applications, Challenges, and Future Directions of Fecal Microbiota Transplantation in Pediatric Disorders.
2026 · cited by 0
A pediatric review confirms that recurrent Clostridioides difficile infection is the primary and best-supported indication for FMT, with high success rates.
Fecal microbiota transplantation: from empirical remedy to precision medicine.
2026 · cited by 0
A review of FMT's evolution details its established and high efficacy in treating recurrent Clostridioides difficile infection.
Blastocystis spp. in fecal microbiota transplantation: Evidence, policy, and the screening paradox.
2026 · cited by 0
A study on donor screening notes that FMT remains an established and successful treatment for recurrent Clostridioides difficile infection despite specific donor parasite screening nuances.
Transplantation of encapsulated fecal microbiota: research progress and future trends.
2026 · cited by 0
A review on encapsulated fecal microbiota confirms significant efficacy of FMT in treating intestinal disorders such as recurrent Clostridioides difficile infection.
Fecal microbiota and microbial community transplantation: <b>a</b> review of current research.
2026 · cited by 0
A review of microbial community transplantation reiterates FMT's role as a successful treatment for Clostridioides difficile infection.