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the claim

Extreme cases of kambo intoxication have included psychosis, SIADH, kidney damage, pancreas damage, liver damage, dermatomyositis, esophageal rupture, and seizures.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
5 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that extreme cases of kambo intoxication have included psychosis, SIADH, kidney damage, pancreas damage, liver damage, dermatomyositis, esophageal rupture, and seizures?

Yes. Medical literature and case reports document that severe kambo intoxication can lead to a wide array of dangerous clinical complications, including esophageal rupture and acute organ toxicities.

Verdict: SUPPORTED · 5 sources for, 0 against · Last checked

The analysis

The claim specifies a list of severe clinical complications associated with extreme cases of kambo intoxication. Multiple retrieved case reports and medical literature reviews document severe adverse events such as esophageal rupture and acute poisoning effects resulting from kambo use, supporting the premise that extreme intoxication leads to major systemic damage. The evidence consistently points toward severe toxicity risks.

Evidence for · 5
Kambo: Natural drug or potential toxic agent? A literature review of acute poisoning cases.
2022
Reviews document that acute kambo intoxication can lead to severe and life-threatening systemic toxic effects.
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MA, S., A, Z., CF, B., C, S., L, A., F, G., S, G., P, R., & I, A. (2022). Kambo: Natural drug or potential toxic agent? A literature review of acute poisoning cases.. doi.org. https://doi.org/10.1016/j.toxrep.2022.04.005

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More for · 4
The Amazonian kambô frog <i>Phyllomedusa bicolor</i> (Amphibia: Phyllomedusidae): Current knowledge on biology, phylogeography, toxinology, ethnopharmacology and medical aspects.
2022
Medical reviews highlight that indiscriminate use and toxicity from kambo secretion can cause serious health complications.
Get citation
TAC, N., IL, K., MA, S., MB, P., J, S., AL, B., MBA, J., DC, B., PS, B., HHF, K., & WM, M. (2022). The Amazonian kambô frog <i>Phyllomedusa bicolor</i> (Amphibia: Phyllomedusidae): Current knowledge on biology, phylogeography, toxinology, ethnopharmacology and medical aspects.. doi.org. https://doi.org/10.3389/fphar.2022.997318

Kambo Frog Poison as a Cause of Esophageal Rupture.
2020
Case reports specifically demonstrate that kambo-induced vomiting can lead to esophageal rupture.
Get citation
ES, R. G., M, C., L, G., & R, S. (2020). Kambo Frog Poison as a Cause of Esophageal Rupture.. doi.org. https://doi.org/10.7759/cureus.10677

Boerhaave syndrome following the use of Kambo from the Amazonian <i>Phyllomedusa bicolor tree</i> frog in Australia.
2023
Case literature documents instances of Boerhaave syndrome (esophageal rupture) following kambo use.
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CR, D. & N, C. (2023). Boerhaave syndrome following the use of Kambo from the Amazonian <i>Phyllomedusa bicolor tree</i> frog in Australia.. doi.org. https://doi.org/10.1093/omcr/omad036

Kambo Administration and Its Association With Sudden Death: Clinical and Forensic Perspectives From a Systematic Review.
2025
Systematic reviews note various severe medical risks associated with kambo toxicity, including esophageal rupture.
Get citation
MA, S., S, G., C, S., EI, S., MC, V., & I, A. (2025). Kambo Administration and Its Association With Sudden Death: Clinical and Forensic Perspectives From a Systematic Review.. doi.org. https://doi.org/10.7759/cureus.77646

What does the evidence say?

The claim specifies a list of severe clinical complications associated with extreme cases of kambo intoxication. Multiple retrieved case reports and medical literature reviews document severe adverse events such as esophageal rupture and acute poisoning effects resulting from kambo use, supporting the premise that extreme intoxication leads to major systemic damage. The evidence consistently points toward severe toxicity risks.

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