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the claim

Depression is associated with a higher risk of developing dementia.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
4 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that depression is associated with a higher risk of developing dementia?

Yes. A review of longitudinal studies reports that late-life depression predicts increased dementia and Alzheimer's risk, with risk rising per depressive symptom, and a 2020 cohort found recent depression associated with roughly doubled Alzheimer's risk. Additional studies link major depression to higher dementia incidence and depression to cognitive complaints.

Verdict: SUPPORTED · 4 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 4
Depression and Risk of Developing Dementia -
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Depression and Risk of Developing Dementia - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1038/nrneurol.2011.60

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More for · 3
Depression and increased risk of Alzheimer’s dementia: Longitudinal analyses of modifiable risk and sex‐related factors
2020
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Kim, D., Wang, R., Kiss, A., Bronskill, S. E., Lanctot, K. L., Herrmann, N., & Gallagher, D. (2020). Depression and increased risk of Alzheimer’s dementia: Longitudinal analyses of modifiable risk and sex‐related factors. doi.org. https://doi.org/10.1002/alz.047436

Antidepressant exposure and long‐term dementia risk in a nationwide retrospective study on elderly patients with major depressive disorder
2025
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Antidepressant exposure and long‐term dementia risk in a nationwide retrospective study on elderly patients with major depressive disorder. (2025). doi.org. https://doi.org/10.1002/alz70860_097934

Association between depression and subjective cognitive complaints in 47 low- and middle-income countries
2022
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Association between depression and subjective cognitive complaints in 47 low- and middle-income countries. (2022). hal.science. https://doi.org/10.1016/j.jpsychires.2022.07.021

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