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Decreased libido is a common adverse reaction reported by women treated with sertraline hydrochloride.

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SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that decreased libido is a common adverse reaction reported by women treated with sertraline hydrochloride?

Yes. Clinical reviews and pharmacovigilance studies consistently indicate that decreased libido and other forms of sexual dysfunction are well-documented adverse reactions associated with selective serotonin reuptake inhibitors like sertraline.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked

Evidence for · 3
Sexual dysfunction associated with selective serotonin reuptake inhibitors in adults with depression: a systematic review and meta-analysis.
2026
A systematic review and meta-analysis evaluating SSRIs indicates that sexual side effects such as reduced sexual satisfaction and sexual desire disorders are commonly associated with their use.
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S, D. F., L, K., P, R., ML, R. U., AC, R. C., VS, D., FR, S., T, C., AJ, G., & MI, d. R. (2026). Sexual dysfunction associated with selective serotonin reuptake inhibitors in adults with depression: a systematic review and meta-analysis.. doi.org. https://doi.org/10.1007/s00228-026-04011-z

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More for · 2
Management of Antidepressant-Induced Sexual Dysfunction: A Literature Review.
2025
A literature review notes that selective serotonin reuptake inhibitors commonly cause sexual side effects including decreased libido, difficulty with arousal, and delayed orgasm.
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FD, T., GH, B., Z, K., & Z, M. (2025). Management of Antidepressant-Induced Sexual Dysfunction: A Literature Review.. doi.org. https://doi.org/10.7759/cureus.90170

Selective serotonin reuptake inhibitor and serotonin-norepinephrine reuptake inhibitor use and sexual dysfunction: a pharmacovigilance analysis.
2026
A pharmacovigilance analysis using the FAERS database demonstrates that sertraline and other SSRIs present a diverse array of sexual dysfunction manifestations.
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M, S., L, H., P, C., L, Z., D, Z., Y, L., & H, L. (2026). Selective serotonin reuptake inhibitor and serotonin-norepinephrine reuptake inhibitor use and sexual dysfunction: a pharmacovigilance analysis.. doi.org. https://doi.org/10.1093/sexmed/qfag008

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