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the claim

Corticoids, oral anticoagulants, and antipsychotics are medications that can interfere with calcium metabolism.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
6 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Corticoids, oral anticoagulants, and antipsychotics are medications that can interfere with calcium metabolism?

Yes. Corticosteroids, oral anticoagulants, and certain psychotropic medications such as antipsychotics are well-documented to interfere with calcium and bone metabolism, leading to increased fracture risk.

Verdict: SUPPORTED · 6 sources for, 0 against · Last checked

The analysis

The retrieved literature consistently supports the claim that various therapeutic classes, including glucocorticoids (corticoids), anticoagulants, and psychotropic/antipsychotic drugs, negatively impact bone health and mineral metabolism.

Evidence for · 6
Clinician's Guide to Prevention and Treatment of Osteoporosis.
2014
Guides from national osteoporosis foundations highlight multiple medication classes affecting bone health.
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F, C., SJ, d. B., MS, L., EM, L., B, T., S, R., & R, L. (2014). Clinician's Guide to Prevention and Treatment of Osteoporosis.. doi.org. https://doi.org/10.1007/s00198-014-2794-2

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More for · 5
An overview and management of osteoporosis.
2017
General osteoporosis overviews acknowledge secondary causes of bone loss including pharmacotherapy.
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T, S., L, Ö., & NÇ, B. (2017). An overview and management of osteoporosis.. doi.org. https://doi.org/10.5152/eurjrheum.2016.048

The clinician's guide to prevention and treatment of osteoporosis.
2022
Updates on osteoporosis emphasize the role of therapeutics and interfering drug classes.
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MS, L., SL, G., KL, I., EM, L., KG, S., AJ, S., & ES, S. (2022). The clinician's guide to prevention and treatment of osteoporosis.. doi.org. https://doi.org/10.1007/s00198-021-05900-y

Medication-Related Impacts on Pediatric Bone Health.
2025
Pediatric literature confirms glucocorticoids and psychotropics adversely affect bone and calcium metabolism.
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C, J., L, V., L, W., & SC, R. (2025). Medication-Related Impacts on Pediatric Bone Health.. doi.org. https://doi.org/10.1016/j.jposna.2025.100262

Prescribing Cascades: An Umbrella Review and Updated Systematic Review.
2026
Reviews on prescribing cascades document the significant skeletal and metabolic impacts of antipsychotics and related agents.
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M, C., S, C., M, Z., F, M., A, P., M, S., A, F., FUS, M., & G, T. (2026). Prescribing Cascades: An Umbrella Review and Updated Systematic Review.. doi.org. https://doi.org/10.1007/s40266-026-01295-9

Polypharmacy and Bone Health in Patients with Type 2 Diabetes Mellitus: A Narrative Review.
2026
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IO, K., SH, M., & MH, A. (2026). Polypharmacy and Bone Health in Patients with Type 2 Diabetes Mellitus: A Narrative Review.. doi.org. https://doi.org/10.11005/jbm.25.975

What does the evidence say?

The retrieved literature consistently supports the claim that various therapeutic classes, including glucocorticoids (corticoids), anticoagulants, and psychotropic/antipsychotic drugs, negatively impact bone health and mineral metabolism.

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