Congenital insensitivity to pain was documented and is extremely rare
the verdict
SUPPORTED
the evidence backs this
confidence 83/100
Congenital insensitivity to pain has been well-documented in medical literature and is universally recognized as an extremely rare condition.
Evidence for · 11
Update Review and Clinical Presentation in Congenital Insensitivity to Pain and Anhidrosis
2015 · cited by 17
States that congenital insensitivity to pain and anhidrosis (CIPA) is an extremely rare syndrome.
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More for · 10
Clinical, genomics and networking analyses of a high-altitude native American Ecuadorian patient with congenital insensitivity to pain with anhidrosis: a case report
2020 · cited by 13
Notes that CIPA is an extremely rare autosomal recessive disorder characterized by insensitivity to pain.
Recurrent Osteomyelitis in a Paediatric Patient with a Novel NTRK1 Mutation: A Case Report on Congenital Insensitivity to Pain with Anhidrosis
2025 · cited by 2
Identifies CIPA as an exceedingly rare genetic disorder characterized by the inability to perceive pain.
Congenital Insensitivity TO Pain: A Case Report
2023 · cited by 1
Describes congenital insensitivity to pain as a rare genetic disorder and references historical documentation beginning in the 1930s.
Congenital Insensitivity to Pain: A Case Study of a Rare Genetic Disorder
2024 · cited by 1
Classifies congenital insensitivity to pain as an exceedingly rare autosomal recessive condition.
First instance of pain in congenital pain insensitivity with anhidrosis.
2025 · cited by 1
Describes a case of a patient known to have congenital insensitivity to pain and notes the syndrome's rarity.
Case Report: Arthroscopic synovectomy and loose body removal for charcot knee in an adolescent with congenital insensitivity to pain with anhidrosis.
2026 · cited by 0
Notes that Charcot neuroarthropathy in adolescents with congenital insensitivity to pain with anhidrosis is exceptionally rare.
Uncovering oral and maxillofacial clues in congenital insensitivity to pain with anhidrosis: what can sibling cases teach us?
2025 · cited by 0
Describes CIPA as an extremely congenital disorder characterized by severe clinical manifestations including pain insensitivity.
A Novel Inflammatory Autoimmune-Like <i>NTRK1</i>-Associated Phenotype in an Adult Man.
2025 · cited by 0
Notes that CIPA is a rare autosomal recessive disorder characterized by congenital analgesia.
Multidisciplinary Approach for Dental Management of Congenital Insensitivity to Pain with Anhidrosis: Clinical Case Report with 12-Month Follow-Up.
2026 · cited by 0
States that congenital insensitivity to pain and anhidrosis is a rare autosomal recessive disorder.
Oral Rehabilitation in Patient With Hereditary Sensory and Autonomic Neuropathy (HSAN) Type V: Clinical Report.