Cognitive learning ability decreases significantly with older age
the verdict
SUPPORTED
the evidence backs this
confidence 90/100
Substantial neurobiological, animal, and human behavioral evidence consistently indicates that cognitive learning and memory abilities decline significantly with older age.
Evidence for · 6
Dopamine D2 receptor mechanisms contribute to age-related cognitive decline: the effects of quinpirole on memory and motor performance in monkeys
1995 · cited by 268
Demonstrates that dopamine depletion in older monkeys contributes significantly to age-related cognitive decline.
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More for · 5
On the Possible Overestimation of Cognitive Decline: The Impact of Age-Related Hearing Loss on Cognitive-Test Performance
2020 · cited by 62
Discusses age-related sensory processing deficits that impact cognitive test performance, noting that aging affects mental abilities.
Age-related decline in visuo-spatial working memory is reflected by dorsolateral prefrontal activation and cognitive capabilities: Running title: Aging effects on visuo-spatial working memory performance and related cerebral oxygenation.
2020 · cited by 33
Shows that older adults exhibit significantly lower visuo-spatial working memory performance and altered cerebral oxygenation compared to young adults.
Age-related decline in cognitive flexibility is associated with the levels of hippocampal neurogenesis
2023 · cited by 27
Finds that older mice display impairments in learning, memory, and cognitive flexibility associated with reduced hippocampal neurogenesis.
Cognitive training of mice attenuates age-related decline in associative learning and behavioral flexibility
2024 · cited by 9
Observes that older mice perform more poorly in working memory and attention tasks compared to younger counterparts.
Sleep Quality Moderates Age-Related Decline in Hippocampal-Dependent Memory in Midlife Adults
2025 · cited by 0
Provides evidence that older age is associated with steeper declines in hippocampal-dependent memory performance, moderated by sleep quality.