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the claim
Chronically elevated cortisol levels are linked to a higher risk of cancer.
the verdict
CONTESTED PARTIAL
Recorded sources
1 source for · 1 against
Is it true that Chronically elevated cortisol levels are linked to a higher risk of cancer?
Partly. One Mendelian randomisation study reports genetically predicted plasma cortisol associated with higher odds of endometrial cancer only, with no evidence for other cancers or overall cancer, while a review notes chronic stress and cancer findings are conflicting and that cortisol is often elevated in patients who already have advanced cancer.
Verdict: CONTESTED PARTIAL · 1 source for, 1 against · Last checked
Evidence for · 1
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Assessing the role of cortisol in cancer: a wide-ranged Mendelian randomisation study - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1038/s41416-021-01505-8
Evidence against · 1
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Frontiers | Interplay between stress and cancer—A focus on inflammation. (n.d.). frontiersin.org. https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2023.1119095/full
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