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the claim

Chagas disease is caused by a parasite and can cause serious heart and stomach problems.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
12 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Chagas disease is caused by a parasite and can cause serious heart and stomach problems?

Yes. The retrieved literature consistently confirms that Chagas disease is caused by the parasite Trypanosoma cruzi and frequently leads to significant cardiac and digestive complications.

Verdict: SUPPORTED · 12 sources for, 0 against · Last checked

The analysis

Every retrieved paper explicitly supports the premise that Chagas disease is caused by Trypanosoma cruzi and results in cardiac and/or gastrointestinal (stomach) pathology.

Evidence for · 12
2016
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Rodriguez, D. A. L., Carmona, F. D., González, C. I., & Martin, J. (2016). Evaluation of VDR gene polymorphisms in Trypanosoma cruzi infection and chronic Chagasic cardiomyopathy. doi.org. https://doi.org/10.1038/srep31263

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More for · 11
2026
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ME, C., TM, C., JLN, S., JBDR, R., IB, D., FBR, O., M, R., LLO, S., LF, S., LP, S., CCO, A., AR, A., IDS, O., AL, G. d. O., LVBD, A., GGM, L., GMES, J., ILS, M., MPD, R., GD, C., A, S., LMD, M., LL, B., FS, M., & RT, F. (2026). IL-33/ST2 Signaling Protects the Heart by Restraining Inflammation and Parasite Burden during <i>Trypanosoma cruzi</i> Experimental Infection.. doi.org. https://doi.org/10.1021/acsinfecdis.5c00859

2026
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MJ, O., A, A., & AM, H. (2026). Long-Term Parasitological Clearance and Cardiac Progression in <i>Trypanosoma cruzi</i> TcI: A Phase-Stratified Cohort from Colombia.. doi.org. https://doi.org/10.3390/tropicalmed11020059

2025
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AC, I., CKV, N., PS, D., CM, A., BC, B., GB, C., JF, V., BSF, S., SG, M., & MBP, S. (2025). Exercise training reduces cardiac fibrosis, promoting improvement in arrhythmias and cardiac dysfunction in an experimental model of chronic chagasic cardiomyopathy.. doi.org. https://doi.org/10.3389/fphys.2025.1558678

2025
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FB, G., B, D., W, S., OA, B., & AR, P. (2025). Bridging the Nervous-Endocrine System and Immune Response, in Human Chagas Disease Pathology.. doi.org. https://doi.org/10.1159/000548813

2026
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TBS, P., ALP, F., DD, S., LDD, F., CELF, P., LCM, V., IC, S., & FLN, S. (2026). A retrospective study on Chagas disease detection and management in Tremedal and Novo Horizonte: Insights prior to the Oxente Chagas Bahia Project.. doi.org. https://doi.org/10.1371/journal.pntd.0014569

2026
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AC, F., GJ, B., R, A., & J, F. T. (2026). Trypanosoma cruzi Cardiomyopathy Diagnosed via Explant Tissue 28S Ribosomal Gene Sequencing Following Orthotopic Heart Transplantation.. doi.org. https://doi.org/10.7759/cureus.112969

2026
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WMD, S., TSF, A., JB, C. N., H, O., MM, T., GABD, S., RC, S., D, C. F., V, R. J., LH, F., & AP, R. (2026). Effects of MK-886, an inhibitor of the 5-lipoxygenase-activating protein, on peripheral blood mononuclear cells from patients with Chagas' heart disease.. doi.org. https://doi.org/10.1590/0037-8682-0130-2026

2026
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LA, D. J., I, M., J, P., M, S., & B, E. (2026). Stage-Informed <i>Trypanosoma cruzi</i> Antigen Selection Enhances Assay Concordance in the Evaluation of Discordant Chagas Disease Serology.. doi.org. https://doi.org/10.3390/microorganisms14091899

2026
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JP, R., HT, A., VV, B., & ALF, C. (2026). Neurochagas: Experimental and human literature of an uncommon entity (Review).. doi.org. https://doi.org/10.3892/mi.2026.320

2025
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AM, H., ACR, R., ARD, C., AS, S., FSNS, M., FM, C., F, M., GMSD, S., HH, V., LF, P., LHC, S., MT, H., PS, d. S., RM, S., SS, X., & MFF, M. (2025). Clinical Protocols for the Initial Evaluation and Follow-Up of Patients with Chronic Chagas Disease: A Proposal for Referral Centers.. doi.org. https://doi.org/10.3390/tropicalmed11010003

2026
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E, D. & C, H. (2026). Epitope mapping of vaccine antigens Tc24 and TSA1 with antibodies from Trypanosoma cruzi-infected patients.. doi.org. https://doi.org/10.1038/s41435-026-00380-8

What does the evidence say?

Every retrieved paper explicitly supports the premise that Chagas disease is caused by Trypanosoma cruzi and results in cardiac and/or gastrointestinal (stomach) pathology.

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