Celiac disease is an autoimmune disorder that primarily targets the small intestine.
Is it true that celiac disease is an autoimmune disorder that primarily targets the small intestine?
Yes. Celiac disease is well established in the literature as an autoimmune and immune-mediated enteropathy that primarily targets and damages the small intestine in response to gluten.
Verdict: SUPPORTED · 3 sources for, 0 against · Last checked
The retrieved papers consistently define celiac disease as an immune-mediated or autoimmune enteropathy causing damage, villous atrophy, and inflammation primarily in the small intestine. There is no evidence refuting this assertion.
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JA, D., A, B., M, C., & JA, M. (2026). Coeliac disease and the intestinal barrier: mechanisms of disruption and strategies for restoration.. doi.org. https://doi.org/10.1136/gutjnl-2025-335373
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F, M. & M, A. (2026). From gluten to therapeutics: molecular mechanisms of celiac disease and emerging alternatives to the gluten-free diet.. doi.org. https://doi.org/10.3389/fphar.2026.1900029
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K, V., C, C., & M, M. (2026). Molecular histomorphometry and the emerging role of transcriptomics in celiac disease diagnosis and therapeutic trials.. doi.org. https://doi.org/10.1080/07853890.2026.2735791
What does the evidence say?
The retrieved papers consistently define celiac disease as an immune-mediated or autoimmune enteropathy causing damage, villous atrophy, and inflammation primarily in the small intestine. There is no evidence refuting this assertion.
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