Blocking all human sweat glands causes fatal hyperthermia
the verdict
SUPPORTED
the evidence backs this
confidence 90/100
Blocking all human sweat glands prevents evaporative cooling, which is the primary mechanism for human heat dissipation and can lead to fatal hyperthermia under heat stress.
Evidence for · 4
Human temperature regulation under heat stress in health, disease, and injury.
2022 · cited by 226
Paper [3] highlights that temperature regulation is a critical homeostatic system relying on heat dissipation mechanisms like sweating to maintain deep body temperature.
See more details
More for · 3
Mechanisms and controllers of eccrine sweating in humans
2009 · cited by 201
Paper [4] notes that evaporative heat loss via sweat secretion is the primary mechanism of heat dissipation in humans, particularly when ambient temperatures are high.
Exertional Heat Stroke
2017 · cited by 40
Paper [7] identifies anhidrosis (lack of sweating) as a major intrinsic risk factor for exertional heat stroke and life-threatening hyperthermia.
Global warming, heat-related illnesses, and the dermatologist.
2021 · cited by 30
Paper [10] explains that eccrine sweating and subsequent evaporation are vital for cooling, and disorders of eccrine function severely impair the skin's capacity to thermoregulate.