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the claim

Bacteria use CRISPR to defend against viruses.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
7 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that bacteria use CRISPR to defend against viruses?

Yes. Multiple peer-reviewed and reference sources state that CRISPR-Cas systems are an adaptive immune system that bacteria (and archaea) use to defend against viruses and plasmids.

Verdict: SUPPORTED · 7 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 7
CRISPR–Cas therapies targeting bacteria
2025
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CRISPR–Cas therapies targeting bacteria. (2025). pasteur.hal.science. https://doi.org/10.1038/s44222-025-00311-8

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More for · 6
CRISPR-Cas Systems: RNA-Mediated Adaptive Immunity in Bacteria and Archaea
2012
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CRISPR-Cas Systems: RNA-Mediated Adaptive Immunity in Bacteria and Archaea. (2012). ebookcentral.proquest.com. https://ebookcentral.proquest.com/lib/kxp/detail.action?docID=1082831

Physical Model of the Immune Response of Bacteria Against Bacteriophage Through the Adaptive CRISPR-Cas Immune System
2014
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Han, P., Niestemski, L. R., Barrick, J. E., & Deem, M. W. (2014). Physical Model of the Immune Response of Bacteria Against Bacteriophage Through the Adaptive CRISPR-Cas Immune System. arxiv.org. https://doi.org/10.1088/1478-3975/10/2/025004

CRISPR-Cas Systems: A Review of their Role as Non-Canonical Antimicrobials to Combat Drug Resistance
2020
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CRISPR-Cas Systems: A Review of their Role as Non-Canonical Antimicrobials to Combat Drug Resistance. (2020). hal.science. https://hal.science/hal-05312716v1

CRISPR-Csx28 forms a Cas13b-activated membrane pore required for robust CRISPR-Cas adaptive immunity
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CRISPR-Csx28 forms a Cas13b-activated membrane pore required for robust CRISPR-Cas adaptive immunity. (n.d.). cir.nii.ac.jp. https://doi.org/10.1101/2021.11.02.466367

Real-Time Observation of Target Search by the CRISPR Surveillance Complex Cascade
2017
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Xue, C., Zhu, Y., Zhang, X., Shin, Y., & Sashital, D. G. (2017). Real-Time Observation of Target Search by the CRISPR Surveillance Complex Cascade. doi.org. https://doi.org/10.1016/j.celrep.2017.11.110

The Fascinating & Controversial New Science of CRISPR
2020
Get citation
David, W. (2020). The Fascinating & Controversial New Science of CRISPR. eric.ed.gov. https://doi.org/10.1525/abt.2020.82.5.279

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