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Antidepressants are an effective treatment for borderline personality disorder.
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CONTESTED PARTIAL
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3 sources for · 6 against
Is it true that antidepressants are an effective treatment for borderline personality disorder?
Partly. Evidence on antidepressants for borderline personality disorder is mixed and partial: one review reports antidepressants effective in older adults alongside DBT, and another finds SSRIs reduce depressed mood, anxiety and anger mainly in those with comorbid affective disorders. However, a systematic review and meta-analysis reports antidepressants do not consistently reduce BPD severity, and a Cochrane review finds SSRIs lack high-level evidence of effectiveness.
Verdict: CONTESTED PARTIAL · 3 sources for, 6 against · Last checked
Evidence for · 3
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Antidepressant. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Antidepressant
Evidence against · 6
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Krawitz, R. & Jackson, W. (2008). Is treatment effective?. doi.org. https://doi.org/10.1093/oso/9780199202966.003.0009
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More for · 2
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Borderline Personality Disorder in Older Adults: A Review of the Diagnostic and Treatment Dilemma. (2024). doi.org. https://doi.org/10.54169/ijocp.v4i02.130
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Pharmacotherapy of borderline personality disorder: a systematic review for publication purpose.. (2012). pubmed.ncbi.nlm.nih.gov. https://pubmed.ncbi.nlm.nih.gov/21728970
More against · 5
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Sercan, M. & Saydam, M. (2021). Psychopharmacological therapy in borderline personality disorder. psychiatry-psychopharmacology.com. https://psychiatry-psychopharmacology.com/index.php/pub/article/view/43
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Antipsychotics, Antidepressants, Anticonvulsants, and Placebo on the Symptom Dimensions of Borderline Personality Disorder. (2011). doi.org. https://doi.org/10.1097/jcp.0b013e31822c1636
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Gartlehner, G., Crotty, K., Kennedy, S., Edlund, M. J., Ali, R., Siddiqui, M., Fortman, R., Wines, R., Persad, E., & Viswanathan, M. (2021). Pharmacological Treatments for Borderline Personality Disorder: A Systematic Review and Meta-Analysis.. doi.org. https://doi.org/10.1007/s40263-021-00855-4
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Borderline personality disorder: current drug treatments and future prospects - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1177/2040622310368455
Pharmacotherapy for borderline personality disorder: Cochrane systematic review of randomised trials
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Pharmacotherapy for borderline personality disorder: Cochrane systematic review of randomised trials. (n.d.). cir.nii.ac.jp. https://doi.org/10.1192/bjp.bp.108.062984
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