Evidence indicates that acrylic and polymeric dental appliances can release residual monomers and chemicals like methyl methacrylate or bisphenol compounds, which may pose localized health risks such as cytotoxicity, allergic sensitization, or soft-tissue irritation.
Evidence for · 3
The Release of Residual Monomeric Methyl Methacrylate from Acrylic Appliances in the Human Mouth: An Assay for Monomer in Saliva
1988 · cited by 107
Paper [0] demonstrates that acrylic appliances release residual methyl methacrylate monomer into saliva, which can potentially sensitize patients or elicit allergic reactions.
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More for · 2
A systematic review of biocompatibility and safety of orthodontic clear aligners and transparent vacuum-formed thermoplastic retainers: Bisphenol-A release, adverse effects, cytotoxicity, and estrogenic effects.
2023 · cited by 25
Paper [5] notes that orthodontic clear aligners and retainers can cause adverse effects such as soft-tissue issues, burning, sore tongue, and potential chemical exposure.
Cytotoxicity and Endocrine Disruption in Materials Used for Removable Orthodontic Retainers: A Comprehensive Review.
2025 · cited by 6
Paper [8] indicates that while retainer materials are generally biocompatible, certain photopolymer resins show cytotoxicity and release bisphenol-type compounds.