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the claim

A ketogenic diet reduces markers of systemic inflammation in humans.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
4 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that a ketogenic diet reduces markers of systemic inflammation in humans?

Yes. A 2024 systematic review and meta-analysis of randomized controlled trials reports that adherence to a ketogenic diet improves some inflammation-related markers, including TNF-α and IL-6, in humans. Additional human and animal studies point in the same direction but cover narrower populations or markers.

Verdict: SUPPORTED · 4 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 4
A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation
2022
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A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation. (2022). doi.org. https://doi.org/10.1038/s42003-023-05478-7

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More for · 3
The effect of a ketogenic diet on inflammation-related markers: a systematic review and meta-analysis of randomized controlled trials
2024
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Ji, J., Fotros, D., Sohouli, M. H., Velu, P., Fatahi, S., & Liu, Y. (2024). The effect of a ketogenic diet on inflammation-related markers: a systematic review and meta-analysis of randomized controlled trials. doi.org. https://doi.org/10.1093/nutrit/nuad175

The role and benefits of ketogenic diet in modulating inflammation in multiple sclerosis: A systematic review and meta-analysis.
2025
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NJ, R., NZY, B., PH, R., A, T., HMA, R., C, S., P, P., Y, T., P, I., & J, J. (2025). The role and benefits of ketogenic diet in modulating inflammation in multiple sclerosis: A systematic review and meta-analysis.. doi.org. https://doi.org/10.1016/j.disamonth.2025.102013

The therapeutic potential of a polyunsaturated fatty acid-enriched high-fat diet in Leigh syndrome: Insights from a preclinical model.
2025
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Willemse, L., Terburgh, K., & Louw, R. (2025). The therapeutic potential of a polyunsaturated fatty acid-enriched high-fat diet in Leigh syndrome: Insights from a preclinical model.. doi.org. https://doi.org/10.1016/j.bbadis.2025.167873

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