Injuries to the arm, forearm or wrist area can lead to various nerve disorders. One such disorder is median nerve palsy. The median nerve controls the Injuries to the arm, forearm or wrist area can lead to various nerve disorders. One such disorder is median nerve palsy. The median nerve controls the majority of the muscles in the forearm. It controls abduction of the thumb, flexion of hand at wrist, flexion of digital phalanx of the fingers, is the sensory nerve for the first three fingers, etc. Because of this major role of the median nerve, i Lack of ability to abduct and oppose the thumb due to paralysis of the thenar muscles. This is called "ape-hand deformity". Sensory loss in the thumbs, index fingers, long fingers, and the radial aspect of the ring fingers. Weakness in forearm pronation and wrist and finger flexion Activities of daily living such as brushing teeth, tying shoes, making phone calls, turning door knobs and writing, may become difficult with a median nerve injury.