Vomiting provides physiological relief from nausea and ingested toxins
the verdict
INSUFFICIENT LEANING
refutedsupported
the weight of evidence
2 sources for · 0 against
The retrieved literature mentions physiological pathways of nausea and vomiting and the role of emetics in toxic ingestion, but lacks explicit evidence proving that vomiting inherently provides physiological relief from nausea and toxins.
This chapter provides an overview of the assessment and management of nausea and vomiting and data on their prevalence. Successful management of these complex symptoms requires an ongoing comprehensive assessment to describe the patient’s experience and associated factors, formulate a symptom diagnosis based on an understanding of likely etiologies, and use appropriate nonpharmacologic and pharmacologic management strategies based on best evidence, expert opinion, and patient acceptability. An understanding of the physiological pathways of vomiting and nausea, and common etiologies, including bowel obstruction, provides an evidence-based management plan. Such interventions include patient education, lifestyle changes, selected integrative therapies, and a review of the mechanisms of action of antiemetics.
Effects of emetic and cathartic agents on the gastrointestinal tract and the treatment of toxic ingestion
## Abstract
Emetic drugs and saline cathartics produce direct or reflex changes in gastrointestinal motility. The changes in gastrointestinal smooth muscle function may be important in the rapid oral or rectal expulsion of gastrointestinal contents, effects which serve as a basis for emetic and cathartic drug use in the treatment of toxic ingestion. Because of difficulties in recording gastrointestinal smooth muscle contractile activity from the intact, unanesthetized animal or man, relatively few studies have attempted to characterize the changes in gastrointestinal motility preceding vomiting. Limited results from past studies and the results of more recent studies employing improved technology suggest that pharmacological activation of the emetic reflex is accompanied by characteristic movements of the stomach and small intestine. The gastric response consists of initial muscle relaxation and an expansion of gastric volume. The intestine responds with a contraction, which begins in the distal ileum and migrates orad over the entire small intestine immediately before active
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