Vaping negatively affects lung function
Multiple studies and systematic reviews indicate that vaping negatively affects lung function, causing airway resistance, inflammation, and reduced respiratory metrics.
The claim is specific, empirical, and falsifiable. A substantial body of retrieved literature across clinical studies, animal models, and systematic reviews consistently demonstrates that e-cigarette use leads to adverse pulmonary effects, inflammation, and impaired lung function parameters. Therefore, the claim is supported by the evidence.
R. Seiler-Ramadas, I. Sandner, S. Haider, I. Grabovac, T. Dorner. Health effects of electronic cigarette (e‑cigarette) use on organ systems and its implications for public health. 2020. https://doi.org/10.1007/s00508-020-01711-z
Reviews literature demonstrating that e-cigarette exposure causes pulmonary stress, inflammation, and impaired pulmonary function.
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Divay Chandra, Rachel F. Bogdanoff, Russell P. Bowler, Kambez H. Benam. Electronic cigarette menthol flavoring is associated with increased inhaled micro and sub-micron particles and worse lung function in combustion cigarette smokers. 2023. https://doi.org/10.1186/s12931-023-02410-9
Finds an association between flavored electronic cigarettes and worse lung function indices such as reduced FEV1.
L. Coppeta, A. Magrini, A. Pietroiusti, S. Perrone. Effects of Smoking Electronic Cigarettes on Pulmonary Function and Environmental Parameters. 2018. https://doi.org/10.2174/1874944501811010360
Shows that active e-cigarette smoking causes slight reductions in main pulmonary function parameters.
Xingyu Wei, A. Iakovou, M. Makaryus, S. Khanijo. Pulmonary Function Testing in Patients With E-Cigarette, or Vaping, Product Use-Associated Lung Injury. 2021. https://doi.org/10.7759/cureus.17019
Indicates that severe vaping-related lung injury (EVALI) leads to persistent reductions in lung diffusion capacity.
Di Wang. The association between e-cigarette use among Chinese college students and lung function and physical activity: A cross-sectional study. 2025. https://doi.org/10.18332/tid/213718
Observes increased peripheral airway resistance and respiratory symptom burdens among young e-cigarette users.
Nasir NI, Ja'afar MH, Ahmad N. Systematic review of lung function assessment among youth and young adults e-cigarette users: Current tools and emerging methods.. 2026. https://doi.org/10.1371/journal.pone.0342500
Systematic review highlights that acute and chronic e-cigarette exposure results in decreased spirometric parameters like FEV1 and FVC.
Gandhi A, Lee CE, Beaumont AL, Ozeki S, Parambil CJ, Bowler RP, Rezaee F. The respiratory epithelium in the era of vaping: insights from <i>in vitro</i>, <i>in vivo</i> and human studies.. 2025. https://doi.org/10.1183/16000617.0256-2024
Notes that both acute and chronic exposure to e-cigarettes are linked to adverse respiratory effects including oxidative stress and airway barrier dysfunction.
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