More for · 3
Role of the Fas/FasL pathway in HIV or SIV disease
2009 · cited by 46
Explains how HIV disease involves progressive quantitative depletion of immune cell subsets, leading to immunodeficiency.
Challenges to Cure: Transmission, Virulence and Pathogenesis of HIV Infection
2018 · cited by 2
Highlights the hallmark of HIV infection as the progressive depletion of CD4 helper T cells resulting in reduced production and increased destruction.
The CARD8 inflammasome drives CD4
<sup>+</sup>
T-cell depletion in HIV-1 infection
2023 · cited by 1
Demonstrates that CD4+ T-cell depletion is the root cause of acquired immunodeficiency syndrome (AIDS).