Transfused blood typically exhibits lower levels of 2,3-DPG due to the depletion of this metabolite during the standard storage period of red blood cells.
The claim is specific and empirical, addressing the biochemical changes in stored blood products (the red blood cell storage lesion). The retrieved literature, specifically papers [0] and [8], directly confirms that red blood cells experience a depletion or lower level of 2,3-DPG during storage prior to transfusion. Therefore, the claim is supported by the evidence.