Toxins can accumulate in the human liver
Toxins such as environmental pollutants, mycotoxins, and drugs can accumulate in or adversely affect the liver, leading to hepatic injury and metabolic disruption.
The retrieved literature contains multiple studies (e.g., papers 1, 2, 6, and 11) demonstrating that various toxins—ranging from mycotoxins and marine toxins to pharmaceutical agents and xenobiotics—can accumulate in or cause toxicity within the liver of humans and animals. Therefore, the claim is supported by the evidence.
Juan Blanco. Accumulation of Dinophysis Toxins in Bivalve Molluscs. 2018. https://doi.org/10.3390/toxins10110453
Discusses how marine toxins accumulate in bivalves and lead to intoxication in consumers.
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Constanze Pietsch, Carsten Schulz, Pere Rovira, Werner Kloas, Patricia Burkhardt-Holm. Organ Damage and Hepatic Lipid Accumulation in Carp (Cyprinus carpio L.) after Feed-Borne Exposure to the Mycotoxin, Deoxynivalenol (DON). 2014. https://doi.org/10.3390/toxins6020756
Shows that feed-borne mycotoxins result in lipid accumulation and liver damage in carp.
Ennab W, Tharwat M, Mousa AA, Liu HY, Al-Rabadi GJ, Baiome BA, Alshanbari FA, Cai D. Gut-liver-hypothalamus axis dysfunction in mycotoxin toxicity: mechanisms and protective roles of natural compounds.. 2026. https://doi.org/10.3389/fvets.2026.1852579
Explains how environmental and microbial toxins translocate to the liver and affect hepatic function.
Garg A, Seshie P, Chouthai A, Raval S, Santharaman A, Manzoor A, Broder A. Amoxicillin-Induced Drug-Induced Liver Injury Superimposed on Acute Hepatitis C Infection in a Patient With Hurler Syndrome: A Diagnostic Challenge Assessed by the Updated RUCAM.. 2026. https://doi.org/10.1155/crhe/5815563
Documents drug-induced liver injury (DILI) caused by xenobiotics and conventional drugs accumulating or causing toxicity in the human liver.
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