Tigers are susceptible to SARS-CoV-2 infection due to conserved ACE2 receptor sequences
the verdict
SUPPORTED
the evidence backs this
confidence 80/100
Tigers are highly susceptible to SARS-CoV-2 infection, with numerous documented natural spillover cases in zoological settings globally.
Evidence for · 4
SARS-CoV-2 Infection And Longitudinal Fecal Screening In Malayan Tigers (
<i>Panthera tigris jacksoni</i>
), Amur Tigers (
<i>Panthera tigris altaica</i>
), And African Lions (
<i>Panthera leo krugeri</i>
) At The Bronx Zoo, New York, USA
2020 · cited by 6
Documents multiple natural infections of Malayan and Amur tigers with SARS-CoV-2 at the Bronx Zoo.
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More for · 3
SARS-CoV-2 outbreak in lions, tigers, and hyenas at Denver Zoo.
2025 · cited by 5
Reviews widespread susceptibility and natural outbreaks of SARS-CoV-2 in tigers and other big cats.
SARS-CoV-2 morbidity, treatment interventions, and vaccination practices in tigers (Panthera tigris ssp) in North American zoos
2024 · cited by 5
Demonstrates through a broad North American zoo survey that tiger infection incidence is high and spans multiple subspecies.
First report of SARS-CoV-2 co-infection with chronic dermatophytosis in a lion (Panthera leo) ex situ at Colombia.
2026 · cited by 0
Reports confirmed natural SARS-CoV-2 infection in large captive felids, reinforcing their high susceptibility.