There are valid metrics for measuring the overall excitation of the central nervous system
the verdict
SUPPORTED
the evidence backs this
confidence 85/100
Multiple clinical and neurophysiological studies confirm that metrics such as electroencephalography (EEG), event-related potentials (ERPs), and electroretinography (ERG) provide valid and quantifiable measures of central nervous system arousal and excitation.
Evidence for · 6
Retinal electrophysiology in central nervous system disorders. A review of human and mouse studies
2023 · cited by 37
Paper [0] discusses functional retinal biomarkers and electroretinography as valid physiological indicators for assessing central nervous system function and pathology.
See more details
More for · 5
Clinical, electrophysiological, and biochemical markers of peripheral and central nervous system disease in canine globoid cell leukodystrophy (Krabbe disease)
2016 · cited by 22
Paper [1] demonstrates that electrophysiological metrics like auditory-evoked responses and nerve conduction velocities provide quantifiable, valid measures of central nervous system disease progression.
The role of resting-state EEG localized activation and central nervous system arousal in executive function performance in children with Attention-Deficit/Hyperactivity Disorder.
2018 · cited by 20
Paper [2] uses resting-state electroencephalogram (RS-EEG) spectral power and alpha band activity as valid metrics for measuring central nervous system arousal and activation.
Effects of Caffeine on Event-Related Potentials and Neuropsychological Indices After Sleep Deprivation
2020 · cited by 16
Paper [3] employs event-related potentials (ERPs) and electroencephalography to measure changes in central nervous system arousal and cognitive efficiency following caffeine and sleep deprivation.
The application of electrophysiological methods to characterize AMPA receptors in dissociated adult rat and non-human primate cerebellar neurons for use in neuronal safety pharmacology assessments of the central nervous system.
2020 · cited by 5
Paper [5] validates in vitro electrophysiological recordings of AMPA receptor currents as reliable readouts for assessing central nervous system pharmacology and drug-induced alterations.
Robo2-Nrxn3 Deficiency: A Molecular Hub Linking Excitation-Inhibition Imbalance to the Pathogenesis of Schizophrenia.
2026 · cited by 1
Paper [8] links neurophysiological measures such as event-related potentials and cortical activation to central nervous system excitation-inhibition balance in clinical and animal models.