There are quasi-healthy methods for temporarily resisting sleep
the verdict
SUPPORTED
the evidence backs this
confidence 92/100
Scientific literature extensively documents various pharmacological agents and stimulants, such as caffeine and wake-promoting compounds, that temporarily and effectively counteract sleepiness and maintain cognitive performance.
Evidence for · 5
Caffeine: Cognitive and Physical Performance Enhancer or Psychoactive Drug?
2014 · cited by 615
Caffeine acts as a psychoactive stimulant and cognitive enhancer primarily by blocking adenosine receptors.
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More for · 4
What Keeps Us Awake: the Neuropharmacology of Stimulants and Wakefulness Promoting Medications
2004 · cited by 313
Various pharmacological agents and stimulants promote wakefulness by modulating neurotransmitter systems.
Sleep in the United States Military
2019 · cited by 178
Targeted pharmacological and non-pharmacological countermeasures can be utilized to optimize performance during sleep deprivation.
Facilitation of Task Performance and Removal of the Effects of Sleep Deprivation by an Ampakine (CX717) in Nonhuman Primates
2005 · cited by 161
Ampakines can successfully alleviate cognitive and behavioral impairments resulting from sleep deprivation.
Sleep waking and neurobehavioural performance
2003 · cited by 123
Countermeasures such as wake-promoting compounds are commonly used to counteract neurobehavioral deficits caused by extended wakefulness.