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the claim

The sex of the parent species determines the species of a hybrid offspring

the verdict
REFUTED
the evidence says no
Recorded sources
0 sources for · 4 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

The species and traits of a hybrid offspring are determined by complex genetic and chromosomal incompatibilities between parental genomes rather than simply the sex of the parent species.

The analysis

The claim states that the sex of the parent species determines the species of a hybrid offspring. None of the retrieved papers support this assertion; instead, they explain hybrid formation, sterility, and divergence through genetic factors, chromosomal pairing failures, meiotic incompatibilities, and gene misregulation (e.g., PRDM9 interactions, karyotype divergence, and Haldane's rule). Therefore, the claim is refuted by the genomic mechanisms of hybridization.

Evidence against · 4
Prdm9 Intersubspecific Interactions in Hybrid Male Sterility of House Mouse.
Recorded source metadata

Mukaj A, Piálek J, Fotopulosova V, Morgan AP, Odenthal-Hesse L, Parvanov ED, Forejt J. Prdm9 Intersubspecific Interactions in Hybrid Male Sterility of House Mouse.. 2020. https://doi.org/10.1093/molbev/msaa167

Paper [0] shows that hybrid sterility in mice is driven by specific allelic incompatibilities such as Prdm9, rather than simply the sex of the parent species.

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More against · 3
Genetic and karyotype divergence between parents affect clonality and sterility in hybrids.
Recorded source metadata

Marta A, Tichopád T, Bartoš O, Klíma J, Shah MA, Bohlen VŠ, Bohlen J, Halačka K, Choleva L, Stöck M, Dedukh D, Janko K. Genetic and karyotype divergence between parents affect clonality and sterility in hybrids.. 2023. https://doi.org/10.7554/elife.88366

Paper [1] demonstrates that hybrid outcomes depend on genomic and karyotype divergence across a phylogenetic spectrum rather than the parental sex determining the offspring species.

Haldane's rule and heterogametic female and male sterility in the mouse
Recorded source metadata

Fred G. Biddle, Brenda A. Eales, Wendy L. Dean. Haldane's rule and heterogametic female and male sterility in the mouse. 1994. https://doi.org/10.1139/g94-027

Paper [2] discusses hybrid sterility and Haldane's rule in terms of heterogamety and genetic interactions, not parental sex determining species outcome.

Male sterility in Drosophila hybrids revealed by a multi-generational transcriptomic analysis of genes and transposable elements in testes.
Recorded source metadata

Bodelón A, Chillida V, de Oliveira DS, Vieira C, Guerreiro MPG. Male sterility in Drosophila hybrids revealed by a multi-generational transcriptomic analysis of genes and transposable elements in testes.. 2026. https://doi.org/10.1186/s12915-026-02566-y

Paper [7] attributes hybrid sterility and incompatibilities to gene misregulation, transposable elements, and transcriptomic changes in crosses.

The paper trail · every fact has a biography
first checked01 Aug 2026
judged → REFUTED · 901 Aug 2026
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