The number of mitochondria in a cell is strictly regulated
the verdict
SUPPORTED
the evidence backs this
confidence 86/100
The number and quality of mitochondria in cells are tightly governed by regulatory networks involving mitochondrial biogenesis, dynamics, and mitophagy.
Evidence for · 6
New Insights into Molecular Mechanisms Mediating Adaptation to Exercise; A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy
2021 · cited by 47
Discusses how mitochondrial biogenesis, mitophagy, and autophagy are regulated to maintain mitochondrial homeostasis.
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More for · 5
Advancing the frontiers of phytotherapy: a comprehensive review of botanical interventions targeting mitochondrial quality control to ameliorate endometriosis.
2026 · cited by 0
Highlights the mitochondrial quality control system, which tightly regulates mitochondrial dynamics, biogenesis, and mitophagy.
Mitochondrial Quality Control in Cardiovascular Disease: A Systematic Review of Mitophagy, Mitochondrial Biogenesis and Therapeutic Modulation
2026 · cited by 0
Emphasizes that mitochondrial quality control, including biogenesis and mitophagy, is essential for cellular energy homeostasis.
Mitochondrial Dysfunction and Diabetic Retinopathy: Research Progress from Pathogenic Mechanisms to Therapeutic Targets.
2026 · cited by 0
Notes that mitochondrial biogenesis and mitophagy are regulated processes that respond to metabolic stress.
SUMOylation in Mitochondrial Quality Control: Mechanisms and Implications for Neurodegenerative Disease.
2026 · cited by 0
Describes how a sophisticated mitochondrial quality control network regulates mitochondrial biogenesis, dynamics, and mitophagy.
The Molecular and Cellular Mechanisms of Melatonin: From Physiological Actions to Clinical Applications in Reproductive Medicine.
2026 · cited by 0
Explains that mitochondrial quality control involves regulated processes such as mitochondrial dynamics, mitophagy, and biogenesis.