The brain avoids pathological feedback loops through inhibitory neural circuits
the verdict
SUPPORTED
the evidence backs this
confidence 96/100
Neurophysiological evidence consistently demonstrates that the brain maintains stable network dynamics and prevents runaway pathological feedback loops through the precise regulation and balance of excitatory and inhibitory neural circuits.
Evidence for · 5
The Variable Discharge of Cortical Neurons: Implications for Connectivity, Computation, and Information Coding
1998 · cited by 2,303
Demonstrates that cortical neurons maintain stable information propagation by balancing excitation and inhibition.
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More for · 4
Neocortical Network Activity<i>In Vivo</i>Is Generated through a Dynamic Balance of Excitation and Inhibition
2006 · cited by 1,000
Shows that spontaneous neocortical network activity relies on a precise and dynamic balance of excitation and inhibition.
What Determines the Frequency of Fast Network Oscillations With Irregular Neural Discharges? I. Synaptic Dynamics and Excitation-Inhibition Balance
2003 · cited by 918
Indicates that the balance between recurrent excitation and inhibition dictates network rhythmogenesis and prevents runaway dynamics.
Circadian dynamics in measures of cortical excitation and inhibition balance
2016 · cited by 77
Highlights how cortical excitation and inhibition balance is regulated over time to maintain proper neural function.
Hopf Bifurcation in Mean Field Explains Critical Avalanches in Excitation-Inhibition Balanced Neuronal Networks: A Mechanism for Multiscale Variability
2020 · cited by 33
Explains how excitation-inhibition balanced networks maintain stable macroscopic states and regulate neural variability.