The assumption of weak selection simplifies mathematical models in population genetics
the verdict
SUPPORTED
the evidence backs this
confidence 85/100
Mathematical models in population genetics frequently invoke the assumption of weak selection (or weak epistasis) to make complex evolutionary dynamics analytically tractable, such as by ignoring linkage disequilibrium or deriving polynomial-time fixation probabilities.
Evidence for · 4
Fixation probabilities in graph-structured populations under weak selection
2021 · cited by 37
Paper [3] derives tractable expressions for fixation probabilities by assuming weak selection, enabling computations on arbitrary graphs.
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More for · 3
Evolutionary dynamics in the two-locus two-allele model with weak selection
2017 · cited by 15
Paper [4] uses weak selection to ignore linkage disequilibrium, making complex two-locus two-allele models analytically tractable.
MULTILOCUS POPULATION GENETICS WITH WEAK EPISTASIS. II. EQUILIBRIUM PROPERTIES OF MULTILOCUS MODELS: WHAT IS THE UNIT OF SELECTION?
1986 · cited by 12
Paper [5] applies perturbation techniques with weak epistasis to simplify multilocus models and determine equilibrium properties.
MULTILOCUS POPULATION GENETICS WITH WEAK EPISTASIS. I. EQUILIBRIUM PROPERTIES OF TWO-LOCUS TWO-ALLELE MODELS
1985 · cited by 8
Paper [6] employs weak epistasis and overdominance assumptions to determine tractable equilibrium properties in two-locus models.