Spike-timing-dependent plasticity is compatible with reciprocal neural connectivity
Multiple computational neuroscience studies successfully incorporate spike-timing-dependent plasticity (STDP) within recurrently connected spiking neural network models, demonstrating that STDP is fully compatible with reciprocal neural connectivity.
The retrieved literature consistently shows that spike-timing-dependent plasticity (STDP) is successfully implemented and studied in spiking neural network models featuring recurrent and reciprocal connectivity (e.g., papers 0, 1, 6, and 10). There are no papers contradicting this compatibility.
Carriere M, Dobler F, Plesser HE, Feledyn A, Tomasello R, Wennekers T, Pulvermüller F. A brain-constrained neural model of cognition and language with NEST: transitioning from the Felix framework.. 2026. https://doi.org/10.1007/s11571-026-10415-5
Paper [0] models brain networks using spiking neurons with recurrent connections and STDP, demonstrating compatibility with complex anatomical connectivity.
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Luboeinski J, Schmitt S, Shafiee S, Hater T, Bösch F, Tetzlaff C. Plastic Arbor: A modern simulation framework for synaptic plasticity-From single synapses to networks of morphological neurons.. 2026. https://doi.org/10.1371/journal.pcbi.1013926
Paper [1] demonstrates that spike-driven plasticity rules like STDP can be successfully implemented in large-scale recurrent networks of biological neurons.
Ruslim MA, Spencer MJ, Hogendoorn H, Meffin H, Lian Y, Burkitt AN. Emergence of sparse coding, balance and decorrelation from a biologically-grounded spiking neural network model of learning in the primary visual cortex.. 2025. https://doi.org/10.1371/journal.pcbi.1013644
Paper [6] shows that recurrent spiking neural networks utilizing STDP rules naturally develop balanced, decorrelated states with robust recurrent connectivity.
Cano G, Kempter R. Conditions for replay of neuronal assemblies.. 2026. https://doi.org/10.1371/journal.pcbi.1013844
Paper [10] explicitly investigates spiking networks with recurrent connectivity, highlighting how intra-assembly recurrent connections support precise spike timing phenomena.
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