Specific levels of alcohol consumption are associated with the onset of Alcohol Use Disorder.
Specific levels and patterns of alcohol consumption are closely associated with the onset and progression of Alcohol Use Disorder.
The retrieved literature consistently supports the association between levels of alcohol consumption (such as frequency, quantity, and duration) and the development or presence of Alcohol Use Disorder (AUD). Multiple studies evaluate consumption biomarkers and problem drinking groups to confirm this relationship, and none of the retrieved papers contradict the premise.
Shaunna L. Clark, Emily E. Hartwell, Doo-Sup Choi, J. Krystal, R. O. Messing, Laura B. Ferguson. Next generation biomarkers for alcohol consumption and alcohol use disorder diagnosis, prognosis, and treatment: A critical review. 2024. https://doi.org/10.1111/acer.15476
This review highlights genetic, epigenetic, and metabolomic research linking alcohol consumption metrics and risk biomarkers to the onset and progression of alcohol-related problems, including AUD.
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Zixuan Zhou, Lan Wang, Wenting Lu, Ling Sun, Fengya Zhen, Shuo Wang, Ran Wang, Mei Song, Yuan-yuan Gao, Xueyi Wang. Prevalence, risk factors, and metabolic implications of alcohol use disorders among male workers in Hebei Province, China: a cross-sectional study. 2025. https://doi.org/10.1186/s13011-025-00669-3
This study demonstrates that problem drinkers exhibit significantly higher alcohol consumption levels—such as intake quantity, frequency, and duration—directly associated with the presence of alcohol use disorders.
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